Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
alphaR | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 |
betaR | 0.00231049060186648 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 | 0.0023105 |
GR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
dR | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 | 1,00E-010 |
alphaS | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 | 0.4 |
betaS | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 1,00E-004 | 5,00E-005 | 1,00E-004 |
alphaS2 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 | 260000 |
betaS2 | 140 | 140 | 140 | 140 | 140 | 140 | 140 | 140 | 140 | 140 | 140 |
GH | 471.854007665112 | 450 | 471.85 | 471.85 | 471.85 | 455 | 480 | 475 | 1491 | 1705 | 1100 |
dH | 4.7E-8 | 4.7E-8 | 4.7E-8 | 4.7E-8 | 4.7E-8 | 5,00E-008 | 4.7E-8 | 4.7E-8 | 4.4E-8 | 4.7E-8 | 4.7E-8 |
LS | 1,69E+006 | 3,60E+006 | 3,40E+006 | 3,40E+006 | 2,50E+006 | 3,90E+006 | 3,30E+006 | 3,10E+006 | 1,20E+006 | 1,20E+006 | 1,66E+006 |
SS | 100 | 130 | 100 | 110 | 100 | 130 | 130 | 130 | 80 | 50 | 80 |
DS | 50 | 50 | 50 | 50 | 50 | 50 | 50 | 50 | 66 | 60 | 50 |
alphaT | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
betaT | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 | 1.1E-6 |
GT | 3,38E-009 | 3.25E-12 | 3.04E-12 | 2.44E-12 | 2.22E-12 | 3.59E-12 | 3.17E-12 | 2.33E-12 | 8.4E-13 | 5.1E-13 | 6.2E-13 |
dT | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 | 2,75 |
alpha31 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 | 0,026 |
beta31 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 | 8,00E-006 |
GD1 | 2,80E-008 | 4,70E-005 | 5,99E-008 | 4,26E-005 | 3,19E-005 | 3,99E-005 | 4,35E-008 | 5,65E-005 | 4,09E-005 | 4,48E-008 | 4,31E-005 |
KM1 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 | 5,00E-007 |
alpha32 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 | 130000 |
beta32 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 | 0.00083 |
GD2 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 | 4,30E-015 |
KM2 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 | 1,00E-009 |
K30 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 |
K31 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 | 2,00E+009 |
K41 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 | 2,00E+010 |
K42 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 | 2,00E+008 |
Tau0R | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 | 1800 |
Tau0S | 120 | 120 | 120 | 120 | 120 | 120 | 120 | 120 | 120 | 120 | 120 |
Tau0S2 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 | 3240 |
Tau0T | 300 | 300 | 300 | 300 | 300 | 300 | 300 | 300 | 300 | 300 | 300 |
Tau03z | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 | 3600 |
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
GD1 | 2,80E-008 | 4,70E-005 | 5,99E-008 | 4,26E-005 | 3,19E-005 | 3,99E-005 | 4,35E-008 | 5,65E-005 | 4,09E-005 | 4,48E-008 | 4,31E-005 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
GT | 3,38E-009 | 3,25E-012 | 3,04E-012 | 2,44E-012 | 2,22E-012 | 3,59E-012 | 3,17E-012 | 2,33E-012 | 8,40E-013 | 5,10E-013 | 6,20E-013 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
betaS | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 2,30E-004 | 1,00E-004 | 5,00E-005 | 1,00E-004 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
GH | 471,8540076651 | 450 | 471,85 | 471,85 | 471,85 | 455 | 480 | 475 | 1491 | 1705 | 1100 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
DS | 50 | 50 | 50 | 50 | 50 | 50 | 50 | 50 | 66 | 60 | 50 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
SS | 100 | 130 | 100 | 110 | 100 | 130 | 130 | 130 | 80 | 50 | 80 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
LS | 1,69E+006 | 3,60E+006 | 3,40E+006 | 3,40E+006 | 2,50E+006 | 3,90E+006 | 3,30E+006 | 3,10E+006 | 1,20E+006 | 1,20E+006 | 1,66E+006 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Standard | Pilo 1 | Pilo 2 | Pilo 6 | Pilo 10 | Pilo 11 | Pilo 12 | Pilo 14 | Kubota 1 | Kubota 2 | Kubota 5 | |
dH | 4,70E-008 | 4,70E-008 | 4,70E-008 | 4,70E-008 | 4,70E-008 | 5,00E-008 | 4,70E-008 | 4,70E-008 | 4,40E-008 | 4,70E-008 | 4,70E-008 |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism | ||
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |
Case No. 1 from Pilo et al. showing slight hyperdeiodination and high conversion rate | Case No. 2 from Pilo et al. showing slight hyperdeiodination | Case No. 6 from Pilo et al. with low secretion rate for T4 | Case No. 10 from Pilo et al. with normal values for SPINA-GT and SPINA-GD | Case No. 11 from Pilo et al. with high secretion rate for T4 | Case No. 12 from Pilo et al. with high production rate for T3 | Case No. 14 from Pilo et al. with low production rate for T3 | Case No. 1 from Kubota et al. showing latent (subclinical) hypothyroidism | Case No. 2 from Kubota et al. showing overt hypothyroidism | Case No. 5 from Kubota et al. showing overt hypothyroidism |